Principal Software Engineer, Instrument Simulations

Your Impact at LILA

Lila Sciences is seeking a Principal Software Engineer, Instrument Simulations to architect and lead the development of our next-generation laboratory automation platform. In this role, you'll be responsible for designing the simulation infrastructure and integration layer that connects AI-driven experimental design with physical robotic systems, enabling closed-loop scientific discovery at unprecedented scale.

What You'll Be Building

• Architect and implement high-fidelity simulation environments that model complex laboratory instrumentation, fluidics, and robotic workflows
• Design robust integration patterns between heterogeneous hardware systems, ensuring reliable and safe execution of fully automated experiments
• Lead the development of APIs and interfaces that enable scientists and AI agents to seamlessly interact with sophisticated automation infrastructure
• Maintain and help establish best practices for hardware-software integration, system monitoring, and CI/CD in laboratory automation contexts for all newly developed systems
• Mentor engineers, likely leading a small agile team

What You’ll Need to Succeed

• Bachelor’s or Master’s degree in Computer Science, Engineering, or a related field: Background that supports technical and leadership capabilities.
• 10+ years of software development experience, including 5+ years in a leadership role: Demonstrates ability to lead and manage complex projects and engineering teams.
• Proven experience in architecting and directing large-scale software projects: Skilled in designing and leading the development of scalable, reliable, and maintainable systems.
• Strong proficiency in programming languages such as C++, Python, or Java: Capable of setting technical standards and guiding development practices.
• Strong record of implementing and advocating for engineering best practices such as code reviews, testing, and continuous integration.
• Experience in leading diverse engineering teams with a focus on collaboration, innovation, and efficiency.
• Excellent strategic thinking skills, with the ability to understand and align team efforts with organizational goals.
• Proven ability to mentor and develop engineering talent, fostering an environment of growth and continuous learning.
• Outstanding communication and interpersonal skills: Effectively engage with stakeholders at all levels, from developers to senior executives.

Bonus Points For

• Ph.D. in Computer Science, Engineering, or a related field
• Experience in leading the development of laboratory automation systems or scientific instrumentation
• Experience with organizational change management and fostering innovation in large technical programs.
• Track record of successful project delivery in agile environments, optimizing team workflows and balancing priorities.
• Published work or presentations that highlight contributions to the field of software engineering and leadership in simulation or automation systems.